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What is hepatic first pass metabolism 2024?

Ruby Turner | 2023-05-05 05:39:17 | page views：1704
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Julian Davis

Works at the International Maritime Organization, Lives in London, UK.
Hepatic first pass effect: All drug dose absorbed from the gastrointestinal tract is first delivered to the liver by the portal vein. A fraction of the drug can then be metabolized in the liver before it even reaches the systemic circulation. Therefore the oral bioavailability of the drug is reduced.
2023-05-12 05:39:17
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Benjamin Smith

QuesHub.com delivers expert answers and knowledge to you.
Hepatic first pass effect: All drug dose absorbed from the gastrointestinal tract is first delivered to the liver by the portal vein. A fraction of the drug can then be metabolized in the liver before it even reaches the systemic circulation. Therefore the oral bioavailability of the drug is reduced.
Metabolism
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