How are worn out red blood cells removed from the circulation 2024?
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Works at the World Health Organization, Lives in Geneva, Switzerland.
Red blood cells (RBC) have a life span of 120 days in humans and about 45 days in mice. Removal of senescent RBC (sRBC) from the circulation occurs through phagocytosis (erythrophagocytosis, EPC), which takes place mainly in macrophages of the spleen, but also in the liver and the bone marrow.
2023-04-29 13:37:33
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Red blood cells (RBC) have a life span of 120 days in humans and about 45 days in mice. Removal of senescent RBC (sRBC) from the circulation occurs through phagocytosis (erythrophagocytosis, EPC), which takes place mainly in macrophages of the spleen, but also in the liver and the bone marrow.