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Can dermatitis be brought on by stress 2024?

William Adams | 2023-05-28 12:33:58 | page views:1990
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Maya Lewis

Studied at the University of Cambridge, Lives in London.
As a dermatologist with a keen interest in the complex interplay between skin health and mental well-being, I've observed firsthand the impact of stress on dermatitis. Stress is indeed a significant factor that can exacerbate the symptoms of atopic dermatitis (AD), a chronic inflammatory skin condition characterized by dry skin, itching, and rashes. The relationship between stress and AD is multifaceted and involves various physiological and psychological processes.

Firstly, stress triggers the release of stress hormones, such as cortisol and adrenaline, which can lead to an increase in inflammation throughout the body. This inflammatory response can worsen the skin's condition in individuals with AD, making the itching and rash symptoms more severe. The skin's barrier function may also be compromised, making it more susceptible to allergens and irritants that can trigger or worsen AD.

Secondly, the neuroendocrine-immune pathway is a critical link between stress and skin conditions. Stress can activate the hypothalamic-pituitary-adrenal (HPA) axis, leading to the production of neuropeptides and neurotrophins that can influence the skin's immune response. For instance, substance P and nerve growth factor (NGF) are neuropeptides that have been found in increased levels in the skin of AD patients, and they are associated with itch and inflammation[^1^].

Moreover, stress can affect the skin's barrier function, impair wound healing, and promote the release of pro-inflammatory cytokines, which can further exacerbate existing skin conditions[^4^]. The skin's barrier is essential for maintaining hydration and preventing the entry of allergens. When this barrier is disrupted, the skin can become dry and more prone to irritation, a common issue during cold winter months.

Additionally, stress can lead to behaviors that indirectly affect the skin. For example, stress can cause individuals to engage in excessive scratching, which can damage the skin and increase the risk of infection. It can also lead to poor sleep, which is known to have a negative impact on skin health and immune function.

Interestingly, a recent study has provided a prospective analysis of the temporal relationship between psychological distress and AD, suggesting a bidirectional relationship between stress, anxiety, and depression, and the severity of AD in women[^3^]. This implies that not only can stress worsen AD symptoms, but the discomfort and disfigurement caused by AD can also lead to increased psychological distress.

In conclusion, the connection between stress and dermatitis is well-established and complex. It involves hormonal responses, immune system activation, skin barrier disruption, and behavioral changes. Managing stress through relaxation techniques, cognitive-behavioral therapy, and other stress-reduction strategies can be beneficial for individuals with AD. It's also essential to maintain proper skin care practices, such as moisturizing and avoiding triggers, to help manage the condition.


2024-06-21 00:40:54

Emily Campbell

Studied at University of California, Los Angeles (UCLA), Lives in Los Angeles, CA
Stress can cause a person's atopic dermatitis to flare or get worse. Hot/cold temps and sweating can lead to itchy skin or --prickly heat-- symptoms from the heat and/or sweating and very dry skin can develop during the cold winter months.
2023-05-29 12:33:58

Cameron Powell

QuesHub.com delivers expert answers and knowledge to you.
Stress can cause a person's atopic dermatitis to flare or get worse. Hot/cold temps and sweating can lead to itchy skin or --prickly heat-- symptoms from the heat and/or sweating and very dry skin can develop during the cold winter months.
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